Corso di Laurea in Infermieristica - Asti

The course contributes to the achievement of the educational objective of the course of study in Nursing Sciences by providing the student with knowledge on cellular functions and the basics of genetics necessary for the understanding of the transmission of hereditary characters and of the main hereditary diseases.

KNOWLEDGE AND UNDERSTANDING

Identify the structures of eukaryotic cells, the cellular devices that operate transport across biological membranes, the structure of nucleic acids and the mechanisms by which duplication, transcription and translation occur. - To classify the different types of mutations and their pathological consequences - Describe and know the principles of Mendelian genetics and the exceptions - Classify and describe, on the basis of their structure and chemical-physical properties, the glycides, lipids, amino acids, proteins and nucleotides

The structure of the eukaryotic cell: the plasma membrane: phospholipids and membrane proteins; the endoplasmic reticulum; the lysosomes; the mitochondria; the nucleus; the cytoskeleton - The transport of molecules and the exchange of information between cell and extracellular environment: cell membranes regulate the passage of substances, the uptake of environmental stimuli and cell adhesion. Examples of cell signaling mediated by hormones and growth factors. - DNA structure and duplication. - Gene expression: the concept of gene and gene expression; transcription of RNA; structure and function of ribosomal RNA, transfer RNA and messenger RNA. Notes on non-coding RNAs and their biological function. - The genetic code and the translation of messenger RNA (protein synthesis). - The structure of chromosomes. Mitosis and Meiosis, cell cycle and its regulation. Cell death. - Mendel's laws. - The hereditary transmission of dominant, recessive and sex-linked genetic traits and related examples of hereditary diseases with these modes of genetic transmission. - The different types of mutations and their molecular and biological consequences.

The Applied Biology module includes: - Frontal lectures in plenary with guided discussion; - Exercises on topics covered in class and solving genetic problems - Individual and group bibliographic searches

The exam consists of a 60-minute written test that students must take for all three modules. For all modules, the written exam consists of an initial part of multiple choice questions covering the topics covered during the lessons, followed by more specific parts with open-ended questions designed to assess the student's degree of preparation and ability. of the student's learning in a comprehensive manner. The written test is followed by an oral interview on the topics covered by the lectures and exercises. The tests will be carried out on the same day. To pass the exam it is necessary to obtain at least 18/30 in all three modules. The final result will be given by the weighted average of the marks obtained in the various modules. The paper is valid for 12 months. It will also be possible to carry out the exams electronically, if necessary.